The GWAS for the AFR sample included 11,920 probable PTSD cases and 39,116 controls (Extended Data Fig. 1 and Supplementary Table 3b) and identified two distinct GWS loci, one on Chr3:1259951, rs4684090 (MAF = 0.04, P = 3.59 × 10−8) intronic to CNTN6, and one on Chr20:6724577, rs112149412 (MAF = 0.02, P = 3.19 × 10−9) near BMP2. GWAS for the 48,221 cases and 217,223 controls in the trans-ancestral analysis (meta-analysis of EUR and AFR samples) (Supplementary Table 3c) identified as GWS SNPs in two of the same regions found GWS in the EUR GWAS: a different lead SNP on Chr7:1959634 (rs137944087, an indel/deletion) in moderate LD with the variant identified in the EUR sample (r2 = 0.38), and a different lead SNP on Chr11:28678870 (rs10767739) in LD with the variant identified in the EUR sample (r2 = 0.54).
