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Chunk #19 — Results — Descriptive

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Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking.
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Allele frequencies were utilized to confirm correct coding of the minor allele for each locus and are presented in Table 1. Frequencies were similar among individual datasets and also to those of the target SNPs in the CEU population in HapMap. The mean AOI for the 15 contributing datasets was 14.4 years (range, 10.9–16.4). The mean AOS for the 39 contributing datasets was 18 years (range, 14.6–21.9).