All groups were included into the comparison of other mental disorders comorbidity during the 5-year follow-up. The results are presented in Table 4. Regarding characteristics of alcohol dependence and associated social and behavioral consequences, the only difference between the 2 groups during the follow-up period was a higher rate of binge drinking in alcohol-dependent bipolar I subjects. Including all groups into the analysis of drug-related characteristics during follow-up, group 4 members reported significantly more often withdrawal symptoms from cocaine and a higher frequency of drug-related treatment than all the other groups.
