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Chunk #14 — Materials and Methods

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Identification of single nucleotide polymorphisms regulating peripheral blood mRNA expression with genome-wide significance: an eQTL study in the Japanese population.
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We also examined whether the eQTL SNPs affecting the expression levels in whole blood also influence expression levels in lymphoblastoid cell lines. The SNPexp [7] software was used to retrieve public data from the HapMap project (release 23) of SNP genotypes and the gene expression levels in lymphoblastoid cell lines of 45 Japanese subjects. Pearson’s correlation coefficients were used to assess the influence of SNPs on expression levels in lymphoblastoid cell lines.