paperKB
coga / coga-kb
Help
Sign in

Chunk #18 — Results

Source
The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies.
Embedded
yes

Text

The effect of the recently described “Long G” (lG) allele was also analyzed [Hu et al., 2006]. The frequency of the “G” allele among the l alleles in the 179 subjects for whom both genotype and expression data for the exon 1 probes was available was 16% (33/211). Using an ordinal regression model that specified the following rank order s,s < s,lG < s,l < l,lG < l,l, there was no effect of the “Long G” allele on transcription using either the exon 1 probe (see data Table III, OLR, P < 0.18) or the exon 8 probe (data not shown).