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Chunk #19 — Results

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The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies.
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Proband gender also had a marked effect on SLC6A4 mRNA production (Fig. 4). Lymphoblast cell lines (the z-score differences reflects an average difference of 0.87 and 0.41 cycles) from males produced 82% and 36% more of exons 1 and 8 transcript, respectively, than the lines from the female subjects.