Chunk #6 — Results — European ancestry GWAS: Substance-specific risk. — Opioid Use Disorder.

Source

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.

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The only significant substance-specific signal for OUD was the well-characterized16 mu opioid receptor (OPRM1) SNP, rs1799971 (p=1.63e-08; Figure 2E). Gene-based analyses produced no significant findings.