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Chunk #47 — 3. Gluconeogenesis — 3.5. Gluconeogenesis—Conclusion

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Role of PPARα in Hepatic Carbohydrate Metabolism.
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cGPDH is the only gluconeogenic gene which was identified to be a direct PPARα target gene. Although PPARα plays a role in fasting-induced stimulation of gluconeogenic gene expression, this may occur via supporting glucocorticoid action rather than direct stimulation of gene transcription.