Furthermore, we verified that GTSE1 overexpression might rescue the LINC00665-mediated reduction in GTSE1 expression. In line with this expectation, the LINC00665+ + GTSE1+ group increased GTSE1 expression compared with the LINC00665+ + GTSE1+-NC group (Figure S4A). Additionally, the LINC00665+ + GTSE1+ group showed an increased proliferation rate, decreased apoptosis rate, and enhanced migration and invasion capacity compared with those of the LINC00665+ + GTSE1+-NC group (Figures S4B–S4D).
