For AAs, family support was not associated with alcohol use across adulthood, whereas friend support was protective against alcohol use in emerging and middle adulthood, above and beyond the effect of age, sex, education, and family income. It is possible that for AAs family support plays a stronger role in alcohol use earlier in development (e.g., adolescence) than in adulthood. We note that family support was negatively correlated with alcohol use among AAs in bivariate correlation analyses. These findings are partially consistent with prior research in AA middle-aged adults, which found that both friend and family emotional support was negatively associated with alcohol use (Boateng-Poku et al., 2020). Our findings also indicated differences in the interaction between alc-PRS and friend support in relation to alcohol use across developmental stages. That is, friend support attenuated genetic risk for alcohol use during middle adulthood but not during emerging or young adulthood. These findings highlight the particularly important role of social support from friends during middle adulthood for AAs. To our knowledge, this is the first study to show developmental differences in the