The Working Group presented its principles and plans, and solicited feedback at an Open Forum at the ACMG Annual Meeting in March, 2012. These principles and plans were further developed based on feedback from ACMG members, and were provisionally reviewed by the ACMG Board in May, 2012 and again in November, 2012. A group of 20 additional experts was nominated by the Working Group members in May, 2012. Fifteen agreed to serve as external reviewers, and feedback from the additional reviewers was solicited in conference calls in June, 2012 and by email in January, 2013. The recommendations and this manuscript were revised based on this feedback. Final approval by the ACMG Board was provided on March 19, 2013.
