paperKB
coga / coga-kb
Help
Sign in

Chunk #46 — Discussion

Source
A multi-omic analysis of the dorsal striatum in an animal model of divergent genetic risk for alcohol use disorder.
Embedded
yes

Text

Rims2, Rimbp2), synaptotagmins (Syt3 and Syt12), syntaxins and related binding proteins, (Stx1b and Stxbp5l), synaptogyrin-1 (Syngr1), bassoon (Bsn), piccolo (Pcl), and amphiphysin (Amph). Differences in the expression or phosphorylation state of these proteins would be expected to alter presynaptic release of neurotransmitters which could contribute to the increased glutamate or GABA signaling previously observed in HAP mice (Fritz et al. 2019).