< .0001) from the model allowing for statistically significant differences across individual items are shown in Table 2. Factor loadings and thresholds could not be constrained across the groups for hazardous use, interpersonal problems, withdrawal, using more than intended, repeated/failed quit attempts, time spent and physical/psychological problems (please see Supplemental eTable 1 for fit indices1). Factor scores that accommodated these differing thresholds and factor loadings were created for each of the four subgroups and used for genomic analyses.
