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Chunk #19 — Results — Effects of Childhood Disorders on Subsequent Substance Use Disorders — Childhood Internalizing and Externalizing Disorders and SUD Outcome

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Psychopathology in offspring from families of alcohol dependent female probands: a prospective study.
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Externalizing disorders, defined by the presence of childhood ADHD or Conduct Disorder, reduced survival time significantly (Wald = 31.94 df =1, p = .000). Because it is not uncommon for individuals to have both externalizing and internalizing disorders, an analysis was completed to evaluate their separate and joint effects on SUD outcome. Presence of both internalizing and externalizing disorder together decreased the age of onset for SUD by young adulthood (Wald = 30.34 df =1, p =0 .001) as seen in Figure 7.