Gender did not significantly influence the age of onset of SUD among the 196 individuals, though as expected familial risk was highly significant (Wald = 15.04, df =1, p =<0.001). To illustrate, by an average of 19.5 years, 15 of the 46 males (32.6%) and 20 of the 57 female high risk offspring (35.1%) met criteria for SUD. In short, risk for Substance Use Disorders by young adulthood appears to be increased for both daughters and sons from multiplex families of maternal alcoholics.
