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Chunk #33 — Results

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Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state.
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Among men, significant PAC differences were found in the delta-gamma M2 cluster, with significantly greater PAC seen in men with AUD (cluster 2: AUD median = 0.7531, unaffected median = 0.745, U = 23568, p = 0.0122, CLES = 0.572, r = 0.144). Compared to candidate and significant PAC clusters from the alpha-gamma and theta-gamma domains, those in the delta-gamma domain were mostly non-overlapping between the sexes. Only women were found to have a significant PAC cluster in the theta-alpha domain (cluster 8: AUD median = 0. 7536, unaffected median = 0. 7464, U = 18749, p = 0.0098, CLES = 0.579, r = 0.157).