Independent samples t-tests revealed that teen binge drinkers exhibited lower (p < 0.01) FA in 18 white matter areas (each ≥27 contiguous voxels) throughout the brain, relative to controls. Table 2 itemizes each area by cluster number while Fig. 1 depicts these regions, including the superior (Clusters 6, 15, 16, and 18) and inferior (Cluster 17) longitudinal fasciculi, corona radiata (Clusters 1, 7, and 14), internal (Cluster 8) and external (Clusters 9 and 10) capsules, corpus callosum (Clusters 2, 3, 4, and 5), cerebellum (Clusters 12 and 13), and limbic projection fibers (Cluster 11). No cluster showed higher FA in bingers than controls. All Hedge's g effect sizes exceeded 1.0 (very large range) for each cluster (see Table 2).
