Altered white matter integrity in adolescent binge drinkers.
paper
Cited
Public
- Authors
- McQueeny, Tim; Schweinsburg, Brian C; Schweinsburg, Alecia D; Jacobus, Joanna; Bava, Sunita; Frank, Lawrence R; Tapert, Susan F
- Year
- 2009
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 19389185
- DOI
- 10.1111/j.1530-0277.2009.00953.x
- PMCID
- PMC2825379
BACKGROUND: White matter integrity has been found to be compromised in adult alcoholics, but it is unclear when in the course of alcohol exposure white matter abnormalities become apparent. This study assessed microstructural white matter integrity among adolescent binge drinkers with no history of an alcohol use disorder. METHODS: We used diffusion tensor imaging to examine fractional anisotropy (FA), a measure of directional coherence of white matter tracts, among teens with (n = 14) and without (n = 14) histories of binge drinking but no history of alcohol use disorder, matched on age, gender, and education. RESULTS: Binge drinkers had lower FA than controls in 18 white matter areas (clusters > or =27 contiguous voxels, each with p < 0.01) throughout the brain, including the corpus callosum, superior longitudinal fasciculus, corona radiata, internal and external capsules, and commissural, limbic, brainstem, and cortical projection fibers, while exhibiting no areas of higher FA. Among binge drinkers, lower FA in 6 of these regions was linked to significantly greater lifetime hangover symptoms and/or higher estimated peak blood alcohol concentrations. CONCLUSIONS: Binge drinking adolescents demonstrated widespread reductions of FA in major white matter pathways. Although preliminary, these results could indicate that infrequent exposure to large doses of alcohol during youth may compromise white matter fiber coherence.
No figures extracted from this document.
1–20 of 20
| Name | Type |
|---|---|
| 3.0-Tesla GE magnetic resonance scanner local | drug |
| adolescent alcohol use | phenotype |
| Adolescent cohort (teens) local | cohort |
| adolescent rats | cohort |
| adolescents | cohort |
| adolescent substance use | phenotype |
| adult alcohol dependence | phenotype |
| adult rats | cohort |
| Adults with alcohol withdrawal seizures local | cohort |
| age | phenotype |
| alcohol | phenotype |
| alcohol dependence | phenotype |
| Alcohol Use Disorder | phenotype |
| alcohol use disorders | phenotype |
| amygdala | anatomy |
| Anterior corona radiata local | anatomy |
| anxiety | phenotype |
| attention deficit hyperactivity disorder | phenotype |
| Axonal atrophy local | phenotype |
| binge alcohol administration local | drug |
| binge drinking | phenotype |
| binge drinking episodes | phenotype |
| binge drinking teens local | cohort |
| blood alcohol concentration (BAC) | phenotype |
| Body of corpus callosum local | anatomy |
| Body of Corpus Callosum local | anatomy |
| body of the corpus callosum local | anatomy |
| Body of the corpus callosum local | anatomy |
| brain damage | phenotype |
| brain development | phenotype |
| brain functioning | phenotype |
| cannabis use | phenotype |
| cannabis use disorder | phenotype |
| cerebellar region | anatomy |
| Cerebellar tracts local | anatomy |
| cerebellum | anatomy |
| cerebrum | anatomy |
| conduct disorder | phenotype |
| control group | cohort |
| controls | cohort |
| Corona radiata local | anatomy |
| corpus callosum | anatomy |
| Corpus callosum body local | anatomy |
| De Bellis 2008 Cohort local | cohort |
| De Bellis 2008 Study local | cohort |
| De Bellis study local | cohort |
| decreased N-acetylaspartate local | phenotype |
| Deep cerebellar nuclei local | anatomy |
| depression | phenotype |
| drinking | phenotype |
| DSM-IV abuse/dependence symptoms local | phenotype |
| duration of drinking local | phenotype |
| Duration of drinking local | phenotype |
| ethanol consumption | phenotype |
| executive functioning | phenotype |
| external capsule | anatomy |
| externalizing disorders | phenotype |
| FA | phenotype |
| FA (body of corpus callosum) local | phenotype |
| FA (fornix/stria terminalis) local | phenotype |
| FA reduction | phenotype |
| Fiber tract quality local | phenotype |
| FMRIB Diffusion Toolbox local | drug |
| Fornix | anatomy |
| Fornix/stria terminalis local | anatomy |
| Fornix/stria terminalis tracts local | anatomy |
| fractional anisotropy | phenotype |
| fractional anisotropy (FA) | phenotype |
| frontal cortex | anatomy |
| Frontal lobe projection fibers local | anatomy |
| frontocerebellar circuitry | anatomy |
| hangover | phenotype |
| Hangover symptoms local | phenotype |
| Hawkins 1992 study local | cohort |
| heavy drinking | phenotype |
| heavy drinking teens local | cohort |
| High-dose alcohol consumption local | phenotype |
| hippocampus | anatomy |
| human adolescents | cohort |
| inferior longitudinal fasciculus | anatomy |
| Inferior peduncle local | anatomy |
| insula | anatomy |
| internal capsule | anatomy |
| internalizing disorders | phenotype |
| intoxication | phenotype |
| learning | phenotype |
| learning and memory | phenotype |
| left anterior corona radiata local | anatomy |
| left inferior cerebellar peduncle local | anatomy |
| left internal capsule local | anatomy |
| left posterior corona radiata local | anatomy |
| lifetime alcohol hangover/withdrawal experiences local | phenotype |
| lifetime drinks local | phenotype |
| Lifetime drinks local | phenotype |
| Limbic projection fibers local | anatomy |
| Low fiber tract coherence local | phenotype |
| major depressive disorder | phenotype |
| major fiber tracts local | anatomy |
| Membrane breakdown local | phenotype |
| memory | phenotype |
| MNI-152 space local | anatomy |
| mood state local | phenotype |
| N-acetylaspartate | drug |
| neurodegeneration | phenotype |
| Neuromaturational processes local | phenotype |
| nicotine | drug |
| nondrinkers local | cohort |
| other drugs | drug |
| parents and youth local | cohort |
| parietal cortex | anatomy |
| participants | cohort |
| Peak blood alcohol concentration local | phenotype |
| peak estimated blood alcohol concentration local | phenotype |
| pons | anatomy |
| postdrinking effects local | phenotype |
| Posterior corona radiata local | anatomy |
| Posterior limb of the internal capsule local | anatomy |
| present study | cohort |
| psychiatric disorders | phenotype |
| Pubertal stage local | phenotype |
| recent substance use local | phenotype |
| reduced FA | phenotype |
| right external capsule local | anatomy |
| risky drinking | phenotype |
| Rostral Body of Corpus Callosum local | anatomy |
| Stria terminalis local | anatomy |
| study cohort | cohort |
| Superior cerebellar peduncle | anatomy |
| superior longitudinal fasciculus | anatomy |
| Tapert 2003 Cohort local | cohort |
| Teenage drinkers local | cohort |
| Teen binge drinkers local | phenotype |
| teens | cohort |
| temporal region | anatomy |
| thalamus | anatomy |
| Total lifetime drinks local | phenotype |
| Tract-Based Spatial Statistics local | drug |
| Viner and Taylor 2007 study local | cohort |
| white matter | anatomy |
| White matter aberrancies local | phenotype |
| whole brain | anatomy |
| Withdrawal experiences local | phenotype |
| Years of alcohol use local | phenotype |
No uploaded files.
Not in any collection.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Joint impact of acute stress and alcohol consumption on neurocognition and addiction vulnerability in adolescence and emerging adulthood: A preregistered systematic review. | Suárez-Suárez S et al. | — | 2026 | → |
| Effects of daridorexant on rest/wake activity patterns and drinking in adult rats exposed to chronic ethanol vapor in adolescence. | Amodeo LR et al. | — | 2025 | → |
| Socioemotional and Executive Control Mismatch in Adolescence and Risks for Initiating Drinking. | Zhao Q et al. | — | 2025 | → |
| Adolescent binge ethanol impacts H3K9me3-occupancy at synaptic genes and the regulation of oligodendrocyte development. | Brocato ER et al. | — | 2024 | → |
| White matter integrity of right frontostriatal circuit predicts internet addiction severity among internet gamers. | Zhou H et al. | — | 2024 | → |
| Characteristics of white matter alterations along fibres in patients with bulimia nervosa: A combined voxelwise and tractography study. | Chen Q et al. | — | 2023 | → |
| Chronic Cocaine Use and White Matter Coherence: A Diffusion Tensor Imaging Study. | Hodges CB et al. | — | 2023 | → |
| Reduced connectivity of the cognitive control neural network at rest in young adults who had their first drink of alcohol prior to age 18. | Jacobson MM et al. | — | 2023 | → |
| Role of deep brain stimulation (DBS) in addiction disorders. | Iqbal J et al. | — | 2023 | → |
| Successful word retraining, maintenance and transference of practice to everyday activities: A single case experimental design in early onset alcohol-induced brain damage. | Savage SA et al. | — | 2023 | → |
| The effects of binge drinking on attention in young adults. | Monds LA et al. | — | 2023 | → |
| Adolescent brain maturation and the neuropathological effects of binge drinking: A critical review. | Tetteh-Quarshie S et al. | — | 2022 | → |
| Areas of Convergence and Divergence in Adolescent Social Isolation and Binge Drinking: A Review. | Lodha J et al. | — | 2022 | → |
| Associations of maternal emotion regulation with child white matter connectivity in Black American mother-child dyads. | Wang C et al. | — | 2022 | → |
| Comparing behavior following binge ethanol in adolescent and adult DBA/2 J mice. | Bent MAM et al. | — | 2022 | → |
| Early developmental alcohol exposure alters behavioral outcomes following adolescent re-exposure in a rat model. | Risbud RD et al. | — | 2022 | → |
| Effect of chronic alcohol intake on the expression of muscle atrophy-related proteins in growing rats. | No SH et al. | — | 2022 | → |
| Effects of binge drinking during adolescence and emerging adulthood on the brain: A systematic review of neuroimaging studies. | Pérez-García JM et al. | — | 2022 | → |
| Peer victimization and associated alcohol and substance use: Prospective pathways for negative outcomes. | Tretyak V et al. | — | 2022 | → |
| Prolonged NoGo P3 latency as a possible neurobehavioral correlate of aggressive and antisocial behaviors: A Go/NoGo ERP study. | Delfin C et al. | — | 2022 | → |
| Structural differences in adolescent brains can predict alcohol misuse | Rane RP et al. | — | 2022 | — |
| Structural differences in adolescent brains can predict alcohol misuse. | Rane RP et al. | — | 2022 | → |
| The Mediating Role of Contextual Problems and Sensation Seeking in the Association between Substance Use and Mental Health in Adolescents from Northern Chile. | Caqueo-Urízar A et al. | — | 2022 | → |
| Using machine learning to determine the shared and unique risk factors for marijuana use among child-welfare versus community adolescents. | Negriff S et al. | — | 2022 | → |
| A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. | Meyers JL et al. | — | 2021 | → |
| Association of Heavy Drinking With Deviant Fiber Tract Development in Frontal Brain Systems in Adolescents. | Zhao Q et al. | — | 2021 | → |
| Consequences of adolescent alcohol use on adult hippocampal neurogenesis and hippocampal integrity. | Wooden JI et al. | — | 2021 | → |
| Endogenous and exogenous opioid effects on oligodendrocyte biology and developmental brain myelination. | Velasco B et al. | — | 2021 | → |
| Sex hormones partially explain the sex-dependent effect of lifetime alcohol use on adolescent white matter microstructure. | Jones SA et al. | — | 2021 | → |
| Suicide Risk and Addiction: The Impact of Alcohol and Opioid Use Disorders. | Rizk MM et al. | — | 2021 | → |
| The persistent impact of adolescent binge alcohol on adult brain structural, cellular, and behavioral pathology: A role for the neuroimmune system and epigenetics. | Coleman LG et al. | — | 2021 | → |
| White matter integrity and functional connectivity in adolescents with a parental history of substance use disorder. | He X et al. | — | 2021 | → |
| White Matter Microstructure in the Young Adult Brain Varies with Neighborhood Disadvantage in Adolescence. | Bell KL et al. | — | 2021 | → |
| Adolescent Substance Use and the Brain: Behavioral, Cognitive and Neuroimaging Correlates. | Hamidullah S et al. | — | 2020 | → |
| Alcohol Induced Brain and Liver Damage: Advantages of a Porcine Alcohol Use Disorder Model. | Shin SK et al. | — | 2020 | → |
| Alterations of Functional Connectivity During the Resting State and Their Associations With Visual Memory in College Students Who Binge Drink. | Kim BM et al. | — | 2020 | → |
| A Neurobiological Model of Alcohol Marketing Effects on Underage Drinking. | Courtney AL et al. | — | 2020 | → |
| Associations between nucleus accumbens structural connectivity, brain function, and initiation of binge drinking. | Morales AM et al. | — | 2020 | → |
| Differential brain responses for perception of pain during empathic response in binge drinkers compared to non-binge drinkers. | Rae CL et al. | — | 2020 | → |
| Effects of early ketamine exposure on cerebral gray matter volume and functional connectivity. | Hung CC et al. | — | 2020 | → |
| Prospective relationships between youth assets, negative life events, and binge drinking in a longitudinal cohort of the youth. | Lensch T et al. | — | 2020 | → |
| PSPH-D-18-00526: Effect of a dual orexin receptor antagonist (DORA-12) on sleep and event-related oscillations in rats exposed to ethanol vapor during adolescence. | Ehlers CL et al. | — | 2020 | → |
| Recent tobacco use has widespread associations with adolescent white matter microstructure. | Thayer RE et al. | — | 2020 | → |
| Sex Differences in the Neurobiology of Alcohol Use Disorder. | Flores-Bonilla A et al. | — | 2020 | → |
| The associations of comorbid substance use disorders and psychiatric conditions with adolescent brain structure and function: A review. | Kroll DS et al. | — | 2020 | → |
| Twenty-first birthday drinking: Extreme-drinking episodes and white matter microstructural changes in the fornix and corpus callosum. | Boness CL et al. | — | 2020 | → |
| Alcohol and delirium tremens: effects of average number of drinks per day and beverage type. | Sørensen HJ et al. | — | 2019 | → |
| Alcohol Use by Youth. | Ryan SA et al. | — | 2019 | → |
| Analysis of brain subnetworks within the context of their whole-brain networks. | Bahrami M et al. | — | 2019 | → |
| Animal models of binge drinking, current challenges to improve face validity. | Jeanblanc J et al. | — | 2019 | → |
| Early life adversity and increased delay discounting: Findings from the Family Health Patterns project. | Acheson A et al. | — | 2019 | → |
| Neurobiological and Cognitive Profile of Young Binge Drinkers: a Systematic Review and Meta-Analysis. | Lees B et al. | — | 2019 | → |
| Nicotine Effects on White Matter Microstructure in Young Adults. | Kangiser MM et al. | — | 2019 | → |
| Sex Differences in the Effect of Alcohol Drinking on Myelinated Axons in the Anterior Cingulate Cortex of Adolescent Rats. | Tavares ER et al. | — | 2019 | → |
| Substance abuse and white matter: Findings, limitations, and future of diffusion tensor imaging research. | Hampton WH et al. | — | 2019 | → |
| The effects of childhood maltreatment on brain structure in adults with eating disorders. | Monteleone AM et al. | — | 2019 | → |
| Young frequent binge drinkers show no behavioral deficits in inhibitory control and cognitive flexibility. | Bensmann W et al. | — | 2019 | → |
| Adolescent alcohol exposure decreases frontostriatal resting-state functional connectivity in adulthood. | Broadwater MA et al. | — | 2018 | → |
| Adolescent brain cognitive development (ABCD) study: Overview of substance use assessment methods. | Lisdahl KM et al. | — | 2018 | → |
| Binge drinking in young people: protocol for a systematic review of neuropsychological, neurophysiological and neuroimaging studies. | Lees B et al. | — | 2018 | → |
| Connecting brain responsivity and real-world risk taking: Strengths and limitations of current methodological approaches. | Sherman L et al. | — | 2018 | → |
| Effect of gabapentin on sleep and delta and theta EEG power in adult rats exposed to chronic intermittent ethanol vapor and protracted withdrawal during adolescence. | Ehlers CL et al. | — | 2018 | → |
| Effects of adolescent alcohol consumption on the brain and behaviour. | Spear LP | — | 2018 | → |
| Effects of Binge Drinking on the Developing Brain: Studies in Humans. | Jones SA et al. | — | 2018 | → |
| Gender Differences in Binge Drinking. | Wilsnack RW et al. | — | 2018 | → |
| Global white matter microstructural abnormalities associated with addiction liability score in drug naïve youth. | Hulvershorn L et al. | — | 2018 | → |
| Role of the innate immune system in the neuropathological consequences induced by adolescent binge drinking. | Pascual M et al. | — | 2018 | → |
| Sexually dimorphic structural abnormalities in major connections of the medial forebrain bundle in alcoholism. | Rivas-Grajales AM et al. | — | 2018 | → |
| Substance-use initiation moderates the effect of stress on white-matter microstructure in adolescents. | Zhai ZW et al. | — | 2018 | → |
| The effects of alcohol hangover on future drinking behavior and the development of alcohol problems. | Courtney KE et al. | — | 2018 | → |
| The involuntary nature of binge drinking: goal directedness and awareness of intention. | Doñamayor N et al. | — | 2018 | → |
| What Predicts What? Self-Reported and Behavioral Impulsivity and High-Risk Patterns of Alcohol Use in Spanish Early Adolescents: A 2-Year Longitudinal Study. | Fernández-Artamendi S et al. | — | 2018 | → |
| Altered white matter integrity in whole brain and segments of corpus callosum, in young social drinkers with binge drinking pattern. | Smith KW et al. | — | 2017 | → |
| Heavy Drinking in College Students Is Associated with Accelerated Gray Matter Volumetric Decline over a 2 Year Period. | Meda SA et al. | — | 2017 | → |
| Hyper-brain connectivity in binge drinking college students: a diffusion tensor imaging study. | Kashfi K et al. | — | 2017 | → |
| MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. | Miguel-Hidalgo JJ et al. | — | 2017 | → |
| Structural neuroimaging correlates of alcohol and cannabis use in adolescents and adults. | Thayer RE et al. | — | 2017 | → |
| The Association of Harsh Parenting, Parent-Child Communication, and Parental Alcohol Use With Male Alcohol Use Into Emerging Adulthood. | Diggs ON et al. | — | 2017 | → |
| The Burden of Binge and Heavy Drinking on the Brain: Effects on Adolescent and Young Adult Neural Structure and Function. | Cservenka A et al. | — | 2017 | → |
| Altered White Matter Microstructure in Adolescents and Adults with Bulimia Nervosa. | He X et al. | — | 2016 | → |
| Binge drinking impacts dorsal striatal response during decision making in adolescents. | Jones SA et al. | — | 2016 | → |
| Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure. | Swartzwelder HS et al. | — | 2016 | → |
| Conduct disorder in females is associated with reduced corpus callosum structural integrity independent of comorbid disorders and exposure to maltreatment. | Lindner P et al. | — | 2016 | → |
| Diffusion tensor imaging reveals adolescent binge ethanol-induced brain structural integrity alterations in adult rats that correlate with behavioral dysfunction. | Vetreno RP et al. | — | 2016 | → |
| Functional and structural brain connectivity of young binge drinkers: a follow-up study. | Correas A et al. | — | 2016 | → |
| Impact of adolescent marijuana use on intelligence: Results from two longitudinal twin studies. | Jackson NJ et al. | — | 2016 | → |
| Landolphia owariensis Attenuates Alcohol-induced Cerebellar Neurodegeneration: Significance of Neurofilament Protein Alteration in the Purkinje Cells. | Oyinbo CA et al. | — | 2016 | → |
| Neurobiological signatures associated with alcohol and drug use in the human adolescent brain. | Silveri MM et al. | — | 2016 | → |
| Prefrontal mechanisms of comorbidity from a transdiagnostic and ontogenic perspective. | Macdonald AN et al. | — | 2016 | → |
| Reflection impulsivity in binge drinking: behavioural and volumetric correlates. | Banca P et al. | — | 2016 | → |
| The impact of ADHD persistence, recent cannabis use, and age of regular cannabis use onset on subcortical volume and cortical thickness in young adults. | Lisdahl KM et al. | — | 2016 | → |
| White matter integrity in young smokers: a tract-based spatial statistics study. | Yu D et al. | — | 2016 | → |
| Abnormal white matter integrity and impairment of cognitive abilities in adolescent inhalant abusers. | Yuncu Z et al. | — | 2015 | → |
| Effects of Emerging Alcohol and Marijuana Use Behaviors on Adolescents' Neuropsychological Functioning Over Four Years. | Nguyen-Louie TT et al. | — | 2015 | → |
| Ethanol intake-induced apoptosis in glial cells and axonal disorders in the cerebellar white matter of UChA rats (voluntary ethanol consumers). | Martinez M et al. | — | 2015 | → |
| Exploratory Analysis of Power Spectrum and Functional Connectivity During Resting State in Young Binge Drinkers: A MEG Study. | Correas A et al. | — | 2015 | → |
| Internet Use and Adolescent Binge Drinking: Findings from the Monitoring the Future Study. | Mu KJ et al. | — | 2015 | → |
| Intertemporal Choice Behavior in Emerging Adults and Adults: Effects of Age Interact with Alcohol Use and Family History Status. | Smith CT et al. | — | 2015 | → |
| Possible confounding factors on cerebral diffusion tensor imaging measurements. | Nenonen M et al. | — | 2015 | → |
| Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. | Kamarajan C et al. | — | 2015 | → |
| Structural connectivity of neural reward networks in youth at risk for substance use disorders. | Squeglia LM et al. | — | 2015 | → |
| Structural reorganization of pyramidal neurons in the medial prefrontal cortex of alcohol dependent rats is associated with altered glial plasticity. | Kim A et al. | — | 2015 | → |
| The association of alcohol outlet density with illegal underage adolescent purchasing of alcohol. | Rowland B et al. | — | 2015 | → |
| The effect of beverage type on alcoholic psychoses rate in Russia. | Razvodovsky YE | — | 2015 | → |
| The National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): A Multisite Study of Adolescent Development and Substance Use. | Brown SA et al. | — | 2015 | → |
| The Power of Theory, Research Design, and Transdisciplinary Integration in Moving Psychopathology Forward. | Vaidyanathan U et al. | — | 2015 | → |
| White matter fractional anisotropy over two time points in early onset schizophrenia and adolescent cannabis use disorder: A naturalistic diffusion tensor imaging study. | Epstein KA et al. | — | 2015 | → |
| Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood. | Gass JT et al. | — | 2014 | → |
| Alcohol binge drinking during adolescence or dependence during adulthood reduces prefrontal myelin in male rats. | Vargas WM et al. | — | 2014 | → |
| Assessment of whole brain white matter integrity in youths and young adults with a family history of substance-use disorders. | Acheson A et al. | — | 2014 | → |
| Associations between alcohol outlet densities and adolescent alcohol consumption: a study in Australian students. | Rowland B et al. | — | 2014 | → |
| Binge drinking in adolescents: a review of neurophysiological and neuroimaging research. | Petit G et al. | — | 2014 | → |
| Brief motivational intervention for adolescents treated in emergency departments for acute alcohol intoxication - a randomized-controlled trial. | Diestelkamp S et al. | — | 2014 | → |
| Contributions of magnetic resonance spectroscopy to understanding development: potential applications in the study of adolescent alcohol use and abuse. | Cohen-Gilbert JE et al. | — | 2014 | → |
| Electrophysiological correlates of alcohol- and non-alcohol-related stimuli processing in binge drinkers: a follow-up study. | Petit G et al. | — | 2014 | → |
| GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies. | Silveri MM | — | 2014 | → |
| Genetic influences on alcohol-related hangover. | Slutske WS et al. | — | 2014 | → |
| Genetics of microstructure of the corpus callosum in older adults. | Kanchibhotla SC et al. | — | 2014 | → |
| Heavy alcohol use, marijuana use, and concomitant use by adolescents are associated with unique and shared cognitive decrements. | Winward JL et al. | — | 2014 | → |
| Larger mid-dorsolateral prefrontal gray matter volume in young binge drinkers revealed by voxel-based morphometry. | Doallo S et al. | — | 2014 | → |
| Neurobiology of adolescent substance use and addictive behaviors: treatment implications. | Hammond CJ et al. | — | 2014 | → |
| Ontogeny and adolescent alcohol exposure in Wistar rats: open field conflict, light/dark box and forced swim test. | Desikan A et al. | — | 2014 | → |
| The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth. | Ewing SW et al. | — | 2014 | → |
| The effect of alcohol use on human adolescent brain structures and systems. | Squeglia LM et al. | — | 2014 | → |
| White Matter and Cognitive Changes in Veterans Diagnosed with Alcoholism and PTSD. | Maksimovskiy AL et al. | — | 2014 | → |
| White matter integrity in alcohol-naive youth with a family history of alcohol use disorders. | Squeglia LM et al. | — | 2014 | → |
| Abnormal white matter integrity and decision-making deficits in alcohol dependence. | Zorlu N et al. | — | 2013 | → |
| Adolescent brain development in normality and psychopathology. | Luciana M | — | 2013 | → |
| Adolescent brain development, substance use, and psychotherapeutic change. | Wetherill R et al. | — | 2013 | → |
| Aerobic exercise moderates the effect of heavy alcohol consumption on white matter damage. | Karoly HC et al. | — | 2013 | → |
| Alcohol use and cerebral white matter compromise in adolescence. | Elofson J et al. | — | 2013 | → |
| Alcohol use disorders in adolescents. | Adger H et al. | — | 2013 | → |
| Associations between fractional anisotropy and problematic alcohol use in juvenile justice-involved adolescents. | Thayer RE et al. | — | 2013 | → |
| A systematic review of diffusion weighted MRI studies of white matter microstructure in adolescent substance users. | Baker ST et al. | — | 2013 | → |
| A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research. | Leeman RF et al. | — | 2013 | → |
| Binge drinking influences the cerebral processing of vocal affective bursts in young adults. | Maurage P et al. | — | 2013 | → |
| Binge drinking trajectory and neuropsychological functioning among university students: a longitudinal study. | Mota N et al. | — | 2013 | → |
| Biological contributions to addictions in adolescents and adults: prevention, treatment, and policy implications. | Potenza MN | — | 2013 | → |
| Brain structural and functional changes in adolescents with psychiatric disorders. | Miguel-Hidalgo JJ | — | 2013 | → |
| Brain structure in adolescents and young adults with alcohol problems: systematic review of imaging studies. | Welch KA et al. | — | 2013 | → |
| Changes in alcohol-related brain networks across the first year of college: a prospective pilot study using fMRI effective connectivity mapping. | Beltz AM et al. | — | 2013 | → |
| Dare to delay? The impacts of adolescent alcohol and marijuana use onset on cognition, brain structure, and function. | Lisdahl KM et al. | — | 2013 | → |
| Drinking history associations with regional white matter volumes in alcoholic men and women. | Ruiz SM et al. | — | 2013 | → |
| Effects of alcohol use initiation on brain structure in typically developing adolescents. | Luciana M et al. | — | 2013 | → |
| Effects of a persistent binge drinking pattern of alcohol consumption in young people: a follow-up study using event-related potentials. | López-Caneda E et al. | — | 2013 | → |
| Increased ventral striatal volume in college-aged binge drinkers. | Howell NA et al. | — | 2013 | → |
| Longitudinal changes in white matter integrity among adolescent substance users. | Bava S et al. | — | 2013 | → |
| Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents. | Fernie G et al. | — | 2013 | → |
| Neuroimaging methods for adolescent substance use disorder prevention science. | Clark DB et al. | — | 2013 | → |
| Neurotoxic effects of alcohol in adolescence. | Jacobus J et al. | — | 2013 | → |
| Not lesser but Greater fractional anisotropy in adolescents with alcohol use disorders. | Cardenas VA et al. | — | 2013 | → |
| Pathways to alcohol-induced brain impairment in young people: a review. | Hermens DF et al. | — | 2013 | → |
| Recent binge drinking predicts smaller cerebellar volumes in adolescents. | Lisdahl KM et al. | — | 2013 | → |
| Substance-use in Childhood and Adolescence: A Brief Overview of Developmental Processes and their Clinical Implications. | Castellanos-Ryan N et al. | — | 2013 | → |
| White matter characterization of adolescent binge drinking with and without co-occurring marijuana use: a 3-year investigation. | Jacobus J et al. | — | 2013 | → |
| White matter integrity is reduced in bulimia nervosa. | Mettler LN et al. | — | 2013 | → |
| White matter integrity pre- and post marijuana and alcohol initiation in adolescence. | Jacobus J et al. | — | 2013 | → |
| White matter integrity, substance use, and risk taking in adolescence. | Jacobus J et al. | — | 2013 | → |
| White matter microstructure, alcohol exposure, and familial risk for alcohol dependence. | Hill SY et al. | — | 2013 | → |
| White matter microstructure alterations: a study of alcoholics with and without post-traumatic stress disorder. | Durkee CA et al. | — | 2013 | → |
| Adolescent brain development and underage drinking in the United States: identifying risks of alcohol use in college populations. | Silveri MM | — | 2012 | → |
| Binge drinking differentially affects adolescent male and female brain morphometry. | Squeglia LM et al. | — | 2012 | → |
| Cerebral effects of binge drinking: respective influences of global alcohol intake and consumption pattern. | Maurage P et al. | — | 2012 | → |
| Frontoparietal connectivity in substance-naïve youth with and without a family history of alcoholism. | Wetherill RR et al. | — | 2012 | → |
| Psychological dysregulation, white matter disorganization and substance use disorders in adolescence. | Clark DB et al. | — | 2012 | → |
| Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. | Leeman RF et al. | — | 2012 | → |
| The influence of gene-environment interactions on the development of alcoholism and drug dependence. | Enoch MA | — | 2012 | → |
| Addiction, adolescence, and the integration of control and motivation. | Gladwin TE et al. | — | 2011 | → |
| Adolescent binge drinking linked to abnormal spatial working memory brain activation: differential gender effects. | Squeglia LM et al. | — | 2011 | → |
| Adolescent C57BL/6J mice show elevated alcohol intake, but reduced taste aversion, as compared to adult mice: a potential behavioral mechanism for binge drinking. | Holstein SE et al. | — | 2011 | → |
| Changes in neuropsychological functioning over 10 years following adolescent substance abuse treatment. | Hanson KL et al. | — | 2011 | → |
| Early adolescent cognitions as predictors of heavy alcohol use in high school. | Andrews JA et al. | — | 2011 | → |
| Extensive abnormality of brain white matter integrity in pathological gambling. | Joutsa J et al. | — | 2011 | → |
| Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain. | Alfonso-Loeches S et al. | — | 2011 | → |
| Neural correlates of verbal learning in adolescent alcohol and marijuana users. | Schweinsburg AD et al. | — | 2011 | → |
| Periadolescent ethanol exposure reduces adult forebrain ChAT+IR neurons: correlation with behavioral pathology. | Ehlers CL et al. | — | 2011 | → |
| The role of early life stress as a predictor for alcohol and drug dependence. | Enoch MA | — | 2011 | → |
| Adolescence as a critical window for developing an alcohol use disorder: current findings in neuroscience. | Nixon K et al. | — | 2010 | → |
| Adolescent brain development and the risk for alcohol and other drug problems. | Bava S et al. | — | 2010 | → |
| A preliminary study of functional magnetic resonance imaging response during verbal encoding among adolescent binge drinkers. | Schweinsburg AD et al. | — | 2010 | → |
| Delay discounting behavior and white matter microstructure abnormalities in youth with a family history of alcoholism. | Herting MM et al. | — | 2010 | → |
| Effects of ethanol on hippocampal function during adolescence: a look at the past and thoughts on the future. | Chin VS et al. | — | 2010 | → |
| Gender differences in the relationship between white matter organization and adolescent substance use disorders. | Thatcher DL et al. | — | 2010 | → |
| Learning and memory performances in adolescent users of alcohol and marijuana: interactive effects. | Mahmood OM et al. | — | 2010 | → |
| Longitudinal characterization of white matter maturation during adolescence. | Bava S et al. | — | 2010 | → |
| MR diffusion tensor imaging: a window into white matter integrity of the working brain. | Chanraud S et al. | — | 2010 | → |
| Neurobiology of the adolescent brain and behavior: implications for substance use disorders. | Casey BJ et al. | — | 2010 | → |
| Neurocognitive correlates of white matter quality in adolescent substance users. | Bava S et al. | — | 2010 | → |
| Research on alcohol and adolescent brain development: opportunities and future directions. | Witt ED | — | 2010 | → |
| Substance use disorders: do males and females have differential vulnerability? | Broome MV et al. | — | 2010 | → |
| Initiating moderate to heavy alcohol use predicts changes in neuropsychological functioning for adolescent girls and boys. | Squeglia LM et al. | — | 2009 | → |
| Underage alcohol use: summary of developmental processes and mechanisms: ages 16-20. | Brown SA et al. | — | 2009 | → |
| White matter integrity in adolescents with histories of marijuana use and binge drinking. | Jacobus J et al. | — | 2009 | → |