Chunk #16 — Results — Differentially Methylated Regions in the NAc Are Associated With Cross-Generational Effects of Adolescent THC Exposure in Adult F1 Offspring
To further reduce the number of low-confidence CpGs, we also excluded sites exhibiting high levels of within group variation (range≥30%), representing approximately one quarter of sites in our data set. Individual inspection of these sites revealed characteristics of underlying genetic variation and technical noise (Supplementary Figure S4), both of which can contribute to inflated between-group differences and spurious statistical associations.
