frequencies used to calculate allele sharing probabilities between relative pairs were estimated using study participants from varying ethnic backgrounds. This approach can lead to biased allele frequency and sharing probabilities amongst minority participants. Thus, analyses were conducted for the full sample as well as restricting the sample to only Caucasian participants. To eliminate the potential for the described bias, results for the Caucasian only sample are reported, though notably only small changes were observed in LOD scores across analyses (ΔLOD < .05 for the variance components analysis and ΔLOD < .4 for the relative pair analysis).
