Fig. 4B illustrates the results of independent analyses in FKBP5 rs3800373 and CRHBP rs7728378 using the derived dichotomous CTQ score. For the sake of simplicity we designated the FKBP5 rs3800373 genotype groups as: major homozygote = FF; minor homozygote + heterozygote = ff. Likewise for the CRHBP rs7728378 genotype groups: major homozygote = CC; minor homozygote + heterozygote = cc. In the case of high childhood trauma, the prevalence of suicide attempt was 0.49 in carriers of the FKBP5 rs3800373 major homozygote (FF) and 0.40 in carriers of the CRHBP rs7728378 major homozygote (CC) whereas the prevalence in carriers of the minor homozygote/heterozygote was 0.28 (ff) and 0.31 (cc) respectively. Without exposure to childhood trauma, genotype had no effect on suicide risk (prevalence = 0.17–0.20).
