In order to test for an additive effect with CRHBP we selected the FKBP5 SNP rs3800373 that had the greatest G × E interactive effect within the logistic regression model (L-R χ2 = 6.6, 1df, p = 0.0103) in our earlier study (Roy et al., 2010). For this analysis we selected CRHBP rs7728378 that showed the strongest G × E result in the current study and in our earlier study (Enoch et al., 2008).
