Scores for the depressed affect cluster were obtained by summing the scores on the four items ‘Do you often feel lonely?’, ‘Do you ever feel ‘just miserable’ for no reason?’, ‘Does your mood often go up and down?’, and ‘Do you often feel ‘fed-up’?’. Scores on the worry cluster were obtained by summing the scores on the four items ‘Are you a worrier?’, ‘Do you suffer from nerves?’, ‘Would you call yourself a nervous person?’, and ‘Would you call yourself tense or highly strung’. Only participants with complete scores on all 4 items were included in GWA analyses of the cluster scores, resulting in sample sizes of N = 361,768 for depressed affect and N = 350,356 for worry.
