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Chunk #25 — RESULTS — Effects of social isolation on endocannabinoid content

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Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats.
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A 2 × 2 ANOVA failed to detect a reliable main effect of isolation rearing on endocannabinoid content. However, social isolation differentially altered endocannabinoid levels based on handling condition in the prefrontal and piriform cortices (see Fig. 6a–l).