matrix proteins, proteases and anti-proteases. Expressed in multiple tissues including brain. SNPs in the close vicinity of this finding showed association at 10−4 in GWAS for bipolar disorder (Sklar et al. 2008). Gene shows association with schizophrenia (Sullivan et al. 2008) and bipolar disorder (Sklar et al. 2008) at P = 10−4 and CNVs in the gene have been noted in a study on autism (Marshall et al. 2008)rs2241685548.11E-062p25.31905000In intron of MYT1L Encodes myelin transcription factor 1-like, a protein of unknown function, which shows expression in brain and other organs. The gene was found disrupted by rare CNVs in schizophrenia patients (Vrijenhoek et al. 2008)rs469727557.54E-065q22.2112270867In intron of REEP5 Encodes the receptor accessory protein 5, expressed in many tissues including brain. The protein may be involved in the transport of G-protein-coupled receptors to the cell membraneAlso lies within suggestive linkage region for ADHD reported in the same publication (Lesch et al. 2008). Association also observed in the 50 K GWAS in the same publicationrs13395022579.68E-062p1279735768In intron of CTNNA2 Encodes catenin alpha 2, expressed in brain and other tissues. The activity of cadherins, which mediate homophilic cell–cell Ca(2+)-dependent association, depends on their anchorage to cytoskeleton via catenins. Catenin alpha 2 functions as a
