the same publicationrs13395022579.68E-062p1279735768In intron of CTNNA2 Encodes catenin alpha 2, expressed in brain and other tissues. The activity of cadherins, which mediate homophilic cell–cell Ca(2+)-dependent association, depends on their anchorage to cytoskeleton via catenins. Catenin alpha 2 functions as a critical agent to regulate the stability of synaptic contacts. Cell-adhesion complexes of catenin alpha 2 with cadherin are likely most important in cerebellar and hippocampal lamination. Finding lies within a linkage region for schizophrenia from meta-analysis (Lewis et al. 2003). Gene shows association with schizophrenia (Sullivan et al. 2008) at p-values of 10−5 and bipolar disorder (Wellcome Trust Case Control Consortium 2007) at 10−4 Gene also shows association with ADHD at 10−4 in GWAS of Neale et al. (2008a)rs10786284611.96E-0610q24.198125495In intron of TLL2 Encodes tolloid-like 2, an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Its function is not clear, but it shows expression in brainThe homologue TLL1 shows association with ADHD and related quantitative traits in the GWAS of Neale et al. (2008a) and Lasky-Su et al. (2008b)rs12453316621.72E-0517q25.169027654Within 83 kb of SDK2 Encodes sidekick homologue 2, a member of the immunoglobulin superfamily. Chicken Sdk2 mediates homophilic adhesion and direct laminar targeting of neuritesrs2237349644.63E-067p15.128729488 CREB5 Encodes cAMP-responsive
