Chunk #13 — Results — Polymorphic CNV Association Analysis of Pack-years of Smoking in AA Subjects

Source

Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study.

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We also looked at COPDGene 6,187 NHW subjects and found there were only 3 hemizygous deletion carriers and one subject with an amplification in 3p26.1 (spanning 1,691 bp from position 6212573 to 6214264, hg18), which shows this CNV component is specific to people of AA ancestry.