The demographic and clinical characteristics of 2,772 normal diploid subjects and 117 subjects with hemizygous deletions (77 of those 117 with larger hemizygous deletions, spanning the significant polymorphic CNV component and 40 other individuals with shorter deletions) are presented in Table 2. We did not observe any significant difference between these two groups of hemizygous deletion carriers for demographic and clinical characteristics. However, the pack-years of smoking was significantly different (p = 0.0006055) between the 77 carriers with larger deletions and the 40 AA subjects carrying smaller deletions.
