T2D, three of these (ADAMTS9, NISCH-STAB1, and ITPR2-SSPN) reaching nominal significance (P < 0.05) (Table 3 and Supplementary Table 5a,b). Because the association signals for correlated traits in this analysis are vulnerable to overestimation given the overlap in GWAS samples examined, we repeated these analyses restricted to our de novo genotyped follow-up studies. Although this also resulted in lower sample size, similar patterns of enrichment were still observed (Supplementary Table 5c).
