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Chunk #65 — STAR* METHODS — QUANTIFICATION AND STATISTICAL ANALYSIS — GTEx gene expression enrichment analysis

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
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MAGMA gene-property analysis (de Leeuw et al., 2015) was performed using gene expression data from 83 tissues based on GTEx RNA-seq data (v7). Expression values (RPKM) were log2 transformed with pseudo-count one after winsorization at 50, and average expression values were taken per tissue. Analysis was performed separately for 30 general tissue types and 53 specific tissue types, and Bonferroni-based multiple testing correction was done for the examined tissue types.