Genomic DNA was extracted from peripheral blood or cell line lymphoblasts using standard protocols. TS subjects and controls were genotyped using the Illumina HumanCNV 370v1-duo, HumanOmni1-Quad, Human1M-Duo v1, and Human 1M-Duo v3 BeadChips, according to the standard Illumina protocol (see Methods in Supplement 1).