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Chunk #6 — METHODS AND MATERIALS — Single Nucleotide Polymorphism (SNP) Genotyping

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Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism.
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Genomic DNA was extracted from peripheral blood or cell line lymphoblasts using standard protocols. TS subjects and controls were genotyped using the Illumina HumanCNV 370v1-duo, HumanOmni1-Quad, Human1M-Duo v1, and Human 1M-Duo v3 BeadChips, according to the standard Illumina protocol (see Methods in Supplement 1).