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Chunk #18 — RESULTS — Exploring the genomic overlap between externalizing and suicide related outcomes

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A Multivariate Genomic Investigation of the Externalizing Spectrum and Suicide Risk.
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was significant (Suicidal ideation: OR = 1.09, 95% CI = 1.05, 1.13; Suicide attempt: OR = 1.20, 95% CI = 1.13, 1.27). For context, Figure 3, Panel B presents the proportion of respondents in COGA reporting a lifetime suicide attempt across deciles of 1) the MVP-EXT PGS and 2) EXT-factor scores derived from the phenotypes used for replication. We see a similar pattern across predictor (PGS vs factor scores) and population, whereby the associations are stronger in EUR-like participants.