et al., 2005; King et al., 1997; McCaul et al., 1991b). It was our original intention to match FHN and FHP women on drinking behavior, by recruiting only light drinkers, as we have successfully done in previous studies (Evans et al., 2000; Evans and Levin, 2003). However, consistent with recent studies, drinking is increasing among women (Keyes et al., 2008), particularly FHP women (LaBrie et al., 2009). We specifically decided not to include moderate drinkers in the FHN group since we have previously shown that the response to alcohol differs between light and moderate female drinkers without a family history of alcoholism (Evans and Levin, 2004). In addition, many other studies, mostly conducted in men or mixed-gender samples (most with unknown family histories of alcoholism), have reported differences between light and moderate drinkers in response to alcohol and other drugs of abuse (e.g., de Wit and Doty, 1994; Holdstock et al., 2000; Stoops et al., 2003; Zacny et al., 2008). Further, a low response to alcohol is also predictive of future alcohol problems, independent of any family history of alcoholism (Schuckit, 1994). Thus, we felt that the most prudent approach was to have a true control group and only include
