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Chunk #1 — INTRODUCTION

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Alcohol use disorder is associated with increases in frontocentral phase-amplitude coupling strength during resting state.
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(MEG) data have been developed (Constable et al., 2013; Wang et al., 2014). AUD-associated changes to FC have been reported using methods such as fMRI seed-based connectivity analyses and EEG coherence (Kamarajan et al., 2020; Kinreich, McCutcheon, et al., 2021; Suk et al., 2021; Woisard et al., 2021), though these measures do not exhaust the ways in which connectivity can be realized. Brain generates oscillations across a wide range of frequencies and neural assemblies operating under different frequency regimes coordinate their activity to achieve functional connectivity (Canolty et al., 2006).