Comparison of the single point analyses is shown in Table III. As the table demonstrates, nominally significant associations or trends for associations for each of the categories of SUD were found at almost every point of the extended region of disequilibrium (see Figure 1) stretching from exon 3 of GABRA2 extending into the intergenic region between GABRA2 and GABRG1 (SNPs 1 to 35). One notable exception to this was at SNP 28 (rs 11503016), which corresponds to the only noted difference between haplotypes 2 and 3 (see Figure 2). Interestingly, that polymorphism was also the only SNP that was nominally significantly associated with either ASPD or MDD with both of the flanking SNPs showing no evidence of association.
