Detailed cohort descriptions, information about cohort-level genotyping and imputation procedures and quality-control filters are provided in Supplementary Tables 8–12. See Supplementary Figure 7 for quantile-quantile plots of the neuroticism and DS meta-analysis results. Association results for the set of approximately independent set of SNPs that attained a p-value smaller than 10−5 are supplied in Supplementary Table 25.