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Chunk #14 — Methods — Statistical Analyses — Genetic Analyses

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The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating.
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In the two-way interaction models, the main effects of genotype (or allele), and impulsivity or dietary restraint were entered in the first step. The second step tested the interaction between genotype and impulsivity or genotype and dietary restraint, while controlling for the main effects of these variables. In the three-way interaction model, the main effects of genotype, impulsivity, and dietary restraint were entered concurrently in the first step. The second step examined the two-way interactions between both genotype and impulsivity and genotype and dietary restraint. Finally, the third step examined the three-way interaction between genotype, impulsivity, and dietary restraint, while partialing out the main effects and 2-way interactions.