paperKB
coga / coga-kb
Help
Sign in

Chunk #13 — Methods — Statistical Analyses — Genetic Analyses

Source
The possible influence of impulsivity and dietary restraint on associations between serotonin genes and binge eating.
Embedded
yes

Text

In this equation, b0 represents the intercept, b1 represents the coefficient for the candidate gene variables, b2 represents the coefficient for the moderator variables, b3 is the coefficient for the 2-way interaction effects, and b4 is the coefficient for the three-way interaction effects. Notably, the candidate gene variables (i.e., 5-HT2a receptor and 5-HTT alleles and genotypes) were effect coded prior to analysis for genotype and the presence vs. absence of the “risk” allele (see Table 2 for a listing of the effect codes). Impulsivity, MEBS Binge Eating, and DEBQ Emotional Eating were standardized through z score transformations prior to analysis. (Note: dietary restraint factor scores were standardized prior to factor analysis). Two-way and 3-way interactions terms were computed by multiplying the independent variables to form interaction terms.