Our haplotypic analysis indicated that carriers of block 1, haplotypes 1 and 4 had lower alcohol “Negative” effects than non-carriers. As expected, carriers of block 1, haplotype 1, a predominantly minor allele haplotype, had concordant results with the analysis of SNPs in this block. Interestingly, carriers of haplotype 4, although a predominantly major allele haplotype, also contained the minor alleles for various SNPs in the haplotype; therefore, these findings are also concordant with the individual SNP analyses.
