Understanding the effects of alcohol abuse on functional connectivity has important implications for the etiology and treatment of alcohol dependence. Given that only a few studies have examined these effects, we sought to examine the association between problem alcohol use and functional connectivity in individuals ranging from binge drinkers to those with severe alcohol use disorder (ALC). As the studies above demonstrated changes in multiple brain networks, we chose to utilize the functionally defined intrinsic connectivity networks (ICNs) defined by Shirer et al. (2012). These fourteen ICNs are comprised of 90 distinct regions of interest (ROIs), or network nodes, that encompass the majority of the cortical and subcortical gray matter (Shirer et al., 2012) and can be mapped to canonical functions: auditory; primary and higher visual; language; sensorimotor; anterior and posterior salience; basal ganglia; dorsal, ventral and precuneus default mode; and bilateral executive control systems (Chakravarthy et al., 2010, Seeley et al., 2007, Damoiseaux et al., 2006, Greicius et al., 2003, Hampson et al., 2006, Smith et al., 2009, Beckmann et al., 2005, Kiviniemi et al., 2009). As long-term heavy
