Finally, we examined the described functional roles of some of the most compelling candidates based on either proximity to the signal or other analyses described in this paper. These uncovered possible roles in adipocyte development (TBX15), pattern formation during embryonic development (HOXC13), angiogenesis (VEGFA, RSPO3, STAB1), Wnt/beta-catenin signaling (RSPO3, KREMEN1), insulin signaling (ADAMTS9, GRB14, NISCH), lipase activity (LYPLAL1), lipid biosynthesis (PIGC) and intracellular calcium signaling (ITPR2) (see Supplementary Note for details).
