Additionally, we performed pathway analyses using the PANTHER database23 based on the same set of 95 genes (Online methods and Supplementary Note). This analysis generated some evidence for over-representation of “developmental processes” (P = 5.8 × 10−8) and “mRNA transcription regulation” (P = 2.7 × 10−6), but neither retained nominal significance after adjustment for bias (e.g. due to non-random SNP coverage in relation to genes) and the number of biological processes tested (Supplementary Note, Supplementary Table 6).
