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Chunk #10 — Materials and Methods — Individual Difference Measures

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The effect of alcohol priming on neural markers of alcohol cue-reactivity.
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To appropriately model the shared variance between the alcohol dependence severity indices and minimize the number of statistical tests, principal components analyses were conducted on the full sample (N=295) to derive factor scores capturing alcoholism severity. The principal factor method (promax oblique rotation) revealed one meaningful factor (first Eigenvalue=2.749, second Eigenvalue=0.858) with each index loading onto the factor at 0.40 or greater (ADS=0.83, PACS=0.74, Symptom Count=0.75, DrInC-2R=0.85, and CIWA-Ar=0.48), and together accounted for 55% of the total variance. Participants’ scores on the single factor (alcoholism severity) were used in subsequent analyses.