With only 128 individuals (2.4% of the total sample), this was the smallest group. Subjects in this group had significantly later onset of first [mean age (SD)=33.7 (10.3)] and heaviest opioid use [mean age (SD)=43 (5.1)] than those in the other groups. Nearly all subjects in this group received a diagnosis of OD, but significantly fewer subjects injected opioids than in Groups 4 and 5. This group had the highest rate of panic disorder but the lowest prevalence of CD, ASPD, social phobia and agoraphobia.