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Chunk #25 — 3. RESULTS — 3.1. Opioid Use and Related Behaviors by Subgroup — 3.1.3. Late-onset heavy opioid users (Group 3)

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Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors.
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With only 128 individuals (2.4% of the total sample), this was the smallest group. Subjects in this group had significantly later onset of first [mean age (SD)=33.7 (10.3)] and heaviest opioid use [mean age (SD)=43 (5.1)] than those in the other groups. Nearly all subjects in this group received a diagnosis of OD, but significantly fewer subjects injected opioids than in Groups 4 and 5. This group had the highest rate of panic disorder but the lowest prevalence of CD, ASPD, social phobia and agoraphobia.