Chunk #57 — Online Methods — Statistical methods — Functional analyses

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Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

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GenomeRunner72 is used to search for enrichment of validated and previously reported sentinel SNVs with histone modification mark genomic features (Supplementary Note). Relevant cardiovascular tissue expression is investigated using Fantom5 reference transcript expression data (fantom.gsc.riken.jp/5) (Supplementary Note).