Chunk #47 — Online Methods — Genome-wide survival association study datasets — (4) Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)
International diagnostic guidelines, including the NINCDS-ADRDA criteria for probable and possible AD and the ADDTC’s State of California criteria for probable and possible vascular dementia (VaD) with or without AD, were followed. CHS identified 3 subtypes: possible/probable AD without VaD (categorized as pure AD, included in all AD) and mixed AD (for cases that met criteria for both AD and VaD, included in all-AD), and, possible/probable VaD without AD (excluded from current study).