Genotyping quality was assessed using previously published methods [13]. Briefly, all SNPs that we called with a genotyping frequency of >99% across individuals (1% rule) were included in the analysis. All participants were also required to have a genotyping success rate of >99% for all SNPs that passed the 1% rule. Finally, each study-wide significant SNP identified in this analysis was manually evaluated in the Illumina Bead Studio files for genotyping quality/accuracy.
