To date, one meta-analysis specifically on disulfiram has been conducted on disulfiram efficacy for the treatment of alcohol use disorder [19]. Of eleven total studies, ten were selected and divided into five forest plots. Not included were trials with co-dependent alcohol and cocaine subjects and trials that combined disulfiram treatment with another treatment (such as a placebo or methadone). They concluded that supervised disulfiram had some effect on short-term abstinence, number of drinking days, and days until relapse compared to placebo, no disulfiram, or other treatments.
