While providing results with useful implications, the Jorgensen et al analysis contained a number of shortcomings regarding content and design issues. Although Jorgensen et al proposed a meta-analysis on disulfiram efficacy, one non-efficacy study was included [20] and five eligible trials were absent [21], [22], [23], [24], [25]. Furthermore, the critical and determinant factor in disulfiram efficacy – that only open-label trials can show efficacy – was not explored by Jorgensen et al, and they mixed open and blind studies in their meta-analysis.
