Haplotype analyses using the Haploview program and our own genotype data indicated that strong LD exists among these nine SNPs, which form a single haplotype block. The haplotype formed by these nine SNPs was also associated with smoking status and cigarette consumption in males, achieving p values of 8.96×10−5 and 6.20×10−3, respectively. Figure 1 presents the structure of the haplotype block formed by these nine SNPs as well as association signals achieved in males for “smoking status” and “cigarette consumption” at these SNPs. (Figure 1 about here)
